Australia and Serbia meet with both having the chance to progress in their final Group D game.
Admittedly, Australia have it all to do if they are to book their place in the knock-out stages in South Africa as, without a win in the tournament so far, the Socceroos require maximum points and results going for them to progress.
If they manage to claim the spoils at the Mbombela Stadium, they need either group leaders Ghana to beat Germany or the opposite result with Joachim Low's side smashing the Black Stars by a big enough margin for Australia to turn around a five-goal difference on the Africans.
Serbia, meanwhile, put their last 16 hopes into their own hands with an impressive win over the Germans in their last outing and victory against the Aussies will assure safe passage to the latter stages of the tournament, although top spot is a long shot unless results go in their favour.
Both sides have had issues with discipline during the World Cup - Australia ended games against Germany and Ghana with 10 men while Serbia have been hand happy in their penalty area not once, but twice to gift penalties to their opposition - the Black Stars took advantage while the Germans fluffed their lines.
Australia, who have had four players sent off in their three World Cup participations, are searching for their first victory in five World Cup games, stretching back to the 2006 finals when they reached the second round before losing to eventual champions Italy.
Serbia do not possess a good record against non-European sides at the World Cup, losing all three of those fixtures and shipping 10 goals in the process.
Serbia coach Radomir Antic is considering resting players on one yellow card for the game in Nelspruit.
The entire first-choice defence - who have kept a clean sheet in six of their last 10 internationals - as well as striker Nikola Zigic and midfielder Zdravko Kuzmanovic are all on a booking so Antic faces the dilemma of stick or twist regarding his starting XI.
Australia boss Pim Verbeek also faces selection issues as suspended duo Harry Kewell and Craig Moore miss the Socceroos' final group game.
Kewell, who remained on the bench against Germany for tactical reasons following Tim Cahill's red card in the opener, followed suit against the Ghanaians as the Galatasaray attacker handballed on the line to deny a goalscoring chance and it remains to be seen whether that will be his last involvement in South Africa.
Moore, Australia's no-nonsense centre-back, will bemissed in the Socceroos' defence as he incurred a one-game suspension for picking up his second yellow card of the tournament in the 1-1 draw in Rustenburg.
Verbeek does have a welcome boost in attacking midfield in the shape of Cahill, who is available for selection after serving his one-match ban.